Almost all animals and at least some beasts and magical beasts (e.g. worgs) leave druids alone and try to avoid them when spotted. However, lizards (at least stone lizards and deep lizards) behave like any hostile NPCs and try to attack as soon as they've spotted you. This could be a feature, but given the wide range of different animals -- including e.g. eels, sharks and even cave bears -- that do "fear" you, it doesn't seem to make much sense.
Even ticks, which according to their description are supposed to be extremely voracious and bloodthirsty creatures, avoid you but a stone lizard won't... this can cause some unintentional animal deaths (or PC deaths) because no matter how fast your fingers are, you don't have time to use animal empathy before the creature attacks you once the domination has run its course. Again, not very intuitive -- but NWN mechanics don't allow you to "renew" animal empathy without the creature first turning hostile.